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1

(+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5 H -benzo[5,6]cyclohepta[1,2- b ]- pyridin-11( R )-yl)-1-piperidinyl]-2-oxo-ethyl]-1-piperidinecarboxamide (SCH-66336): A Very Potent Farnesyl Protein Transferase Inhibitor as a Novel Antitumor Agent

Njoroge, F. George, Taveras, Arthur G., Kelly, Joseph, Remiszewski, Stacy, Mallams, Alan K., Wolin, Ronald, Afonso, Adriano, Cooper, Alan B., Rane, Dinananth F., Liu, Yi-Tsung, Wong, Jesse, Vibulbhan,

Journal:

Journal of Medicinal Chemistry

Année:

1998

Langue:

english

Fichier:

PDF, 404 KB

english, 1998

2

Fast-atom bombardment and tandem mass spectrometry of macrolide antibiotics

Ronald L. Cerny, Denise K. MacMillan, Michael L. Gross, Alan K. Mallams, Birendra N. Pramanik

Journal:

Journal of the American Society for Mass Spectrometry

Année:

1994

Langue:

english

Fichier:

PDF, 765 KB

english, 1994

3

Structural basis for RNA-duplex recognition and unwinding by the DEAD-box helicase Mss116p

Mallam, Anna L., Del Campo, Mark, Gilman, Benjamin, Sidote, David J., Lambowitz, Alan M.

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.83 MB

english, 2012

4

Semisynthetic aminoglycoside antibacterials. Part 10. Synthesis of novel 1-N-aminoalkoxycarbonyl and 1-N-aminoalkylcarboxamido derivatives of sisomicin, gentamicin B, gentamicin C1a, and kanamycin A

Mallams, Alan K., Morton, James B., Reichert, Paul

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1981

Langue:

english

Fichier:

PDF, 3.15 MB

english, 1981

5

Mass spectral studies on aminocyclitol?aminoglycoside antibiotics

Daniels, Peter J. L., Mallams, Alan K., Weinstein, Jay, Wright, John J., Milne, George W. A.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1976

Langue:

english

Fichier:

PDF, 1.20 MB

english, 1976

6

Semisynthetic aminoglycoside antibacterials. Part II. Synthesis of gentamicin X2 and related compounds

Kugelman, Max, Mallams, Alan K., Vernay, H. Frederick, Crowe, David F., Detre, George, Tanabe, Masato, Yasuda, Dennis M.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1976

Langue:

english

Fichier:

PDF, 2.56 MB

english, 1976

7

Novel 3-O-?-L-cladinosyl sixteen-membered macrolide antibacterials

Mallams, Alan K., Rossman, Randall R.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1989

Langue:

english

Fichier:

PDF, 962 KB

english, 1989

8

Tricyclic Farnesyl Protein Transferase Inhibitors: Crystallographic and Calorimetric Studies of Structure−Activity Relationships †

Strickland, Corey L., Weber, Patricia C., Windsor, William T., Wu, Zhen, Le, Hung V., Albanese, Margaret M., Alvarez, Carmen S., Cesarz, David, del Rosario, Joycelyn, Deskus, Jeffrey, Mallams, Alan K.

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 255 KB

english, 1999

9

Kijanimicin. 2. Structure and absolute stereochemistry of kijanimicin

Mallams, Alan K., Puar, Mohindar S., Rossman, Randall R., McPhail, Andrew T., Macfarlane, Ronald D.

Journal:

Journal of the American Chemical Society

Année:

1981

Langue:

english

Fichier:

PDF, 530 KB

english, 1981

10

Megalomicins. 6. Tertiary glycosidic macrolide antibiotics. A structural revision by carbon-13 nuclear magnetic resonance and x-ray crystallography

Ton That Thang,, Lukacs, Gabor, Omura, Satoshi, Bartner, Peter, Boxler, Dena L., Brambilla, Raymond, Mallams, Alan K., Morton, James B., Reichert, Paul

Journal:

Journal of the American Chemical Society

Année:

1978

Langue:

english

Fichier:

PDF, 487 KB

english, 1978

11

Semisynthetic aminoglycoside antibacterials. 6. Synthesis of sisomicin, antibiotic G-52, and novel 6'-substituted analogs of sisomicin from aminoglycoside 66-40C

Davies, D. Huw, Mallams, Alan K., Counelis, Mae, Loebenberg, David, Moss, Eugene L., Waitz, J. Allan

Journal:

Journal of Medicinal Chemistry

Année:

1978

Langue:

english

Fichier:

PDF, 679 KB

english, 1978

12

Structure of sisomicin, a novel unsaturated aminocyclitol antibiotic from Micromonospora inyoensis

Reimann, Hans, Cooper, David J., Mallams, Alan K., Jaret, Robert S., Yehaskel, Albert, Kugelman, Max, Vernay, H. Frederick, Schumacher, Doris

Journal:

Journal of Organic Chemistry

Année:

1974

Langue:

english

Fichier:

PDF, 879 KB

english, 1974

13

Kijanimicin. 1. Structures of the individual sugar components

Mallams, Alan K., Puar, Mohindar S., Rossman, Randall R.

Journal:

Journal of the American Chemical Society

Année:

1981

Langue:

english

Fichier:

PDF, 356 KB

english, 1981

14

Inhibitors of Farnesyl Protein Transferase. 4-Amido, 4-Carbamoyl, and 4-Carboxamido Derivatives of 1-(8-Chloro-6,11-dihydro-5 H -benzo[5,6]- cyclohepta[1,2- b ]pyridin-11-yl)piperazine and 1-(3-Bromo-8-chloro-6,11- dihydro-5 H -benzo[5,6]cyclohepta[1,2- b ]pyridin-11-yl)piperazine 1

Mallams, Alan K., Rossman, Randall R., Doll, Ronald J., Girijavallabhan, Viyyoor M., Ganguly, Ashit K., Petrin, Joanne, Wang, Lynn, Patton, Robert, Bishop, W. Robert, Carr, Donna M., Kirschmeier, Paul

Journal:

Journal of Medicinal Chemistry

Année:

1998

Langue:

english

Fichier:

PDF, 391 KB

english, 1998

15

Megalomicins. II. Structure of megalomicin A

Mallams, Alan K., Jaret, Robert S., Reimann, Hans

Journal:

Journal of the American Chemical Society

Année:

1969

Langue:

english

Fichier:

PDF, 370 KB

english, 1969

16

Megalomicins. I. d-Rhodosamine, a new dimethylamino sugar

Mallams, Alan K.

Journal:

Journal of the American Chemical Society

Année:

1969

Langue:

english

Fichier:

PDF, 285 KB

english, 1969

17

Structures of the aminoglycoside antibiotics 66?40B and 66?40D produced by Micromonospora inyoensis

Davies, D. Huw, Greeves, Diane, Mallams, Alan K., Morton, James B., Tkach, Richard W.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1975

Langue:

english

Fichier:

PDF, 660 KB

english, 1975

18

Structure of aminoglycoside 66-40 C, a novel unsaturated imine produced by Micromonospora inyoensis

Davies, D. Huw, Mallams, Alan K., McGlotten, James, Morton, James B., Tkach, Richard W.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1977

Langue:

english

Fichier:

PDF, 633 KB

english, 1977

19

Synthesis of methyl gentosaminide, methyl 3-deoxy-3-methylaminoarabinopyranoside, and related amino-sugars

Cooper, David J., Davies, D. Huw, Mallams, Alan K., Yehaskel, Albert S.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1975

Langue:

english

Fichier:

PDF, 647 KB

english, 1975

20

Semisynthetic macrolide antibacterials derived from tylosin. Synthesis of 23-O-demycinosyltylosin and related compounds

Mallams, Alan K., Rossman, Randall R.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1989

Langue:

english

Fichier:

PDF, 1.33 MB

english, 1989

21

Synthesis of 3-amino-2,3-dideoxy-?-D-arabino-hexopyranosyl gentamine C1

Daniels, Peter J. L., Mallams, Alan K., Wright, John J.

Journal:

Journal of the Chemical Society Chemical Communications

Année:

1973

Langue:

english

Fichier:

PDF, 185 KB

english, 1973

22

Semisynthetic aminoglycoside antibacterials. Part IV. Synthesis of antibiotic JI-20A, gentamicin B, and related compounds

Kugelman, Max, Mallams, Alan K., Vernay, H. Frederick

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1976

Langue:

english

Fichier:

PDF, 1.41 MB

english, 1976

23

Semisynthetic aminoglycoside antibacterials. Part V. Synthesis of pentosyl and related derivatives of garamine

Mallams, Alan K., Saluja, Surinderjit S., Crowe, David F., Detre, George, Tanabe, Masato, Yasuda, Dennis M.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1976

Langue:

english

Fichier:

PDF, 1.64 MB

english, 1976

24

Semisynthetic aminoglycoside antibacterials. Part I. Preparation of selectively protected garamine derivatives

Kugelman, Max, Mallams, Alan K., Vernay, H. Frederick, Crowe, David F., Tanabe, Masato

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1976

Langue:

english

Fichier:

PDF, 1.39 MB

english, 1976

25

Semisynthetic macrolide antibacterials derived from tylosin. Synthesis of 3-O-acetyl-23-O-demycinosyl-4?-O-isovaleryltylosin and related compounds, as well as the 12,13-epoxy derivatives

Fishman, Andrew G., Mallams, Alan K., Rossman, Randall R.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1989

Langue:

english

Fichier:

PDF, 1.41 MB

english, 1989

26

Semisynthetic aminoglycoside antibacterials. Part III. Synthesis of analogues of gentamicin X2 modified at the 3?-position

Kugelman, Max, Mallams, Alan K., Vernay, H. Frederick

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1976

Langue:

english

Fichier:

PDF, 2.03 MB

english, 1976

27

The megalomicins. Part 7. A structural revision by carbon-13 nuclear magnetic resonance and X-ray crystallography. Synthesis and conformational analysis of 3-dimethylamino- and 3-azido-D- and -L-hexopyranosides, and the crystal structure of 4?-O-(4-lodobenzoyl)megalomicin A

Bartner, Peter, Boxler, Dena L., Brambilla, Raymond, Mallams, Alan K., Morton, James B., Reichert, Paul, Sancilio, Frederick D., Surprenant, Henry, Tomalesky, Gregory, Lukacs, Gabor, Olesker, Alain, T

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1979

Langue:

english

Fichier:

PDF, 3.35 MB

english, 1979

28

Evolution of RNA-Protein Interactions: Non-Specific Binding Led to RNA Splicing Activity of Fungal Mitochondrial Tyrosyl-tRNA Synthetases

Lamech, Lilian T., Mallam, Anna L., Lambowitz, Alan M., Herschlag, Daniel

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 5.01 MB

english, 2014

29

Carotenoids and related compounds. Part 38. Synthesis of (3RS,3?RS)-alloxanthin and other acetylenes

Davies, Anthony J., Khare, Anakshi, Mallams, Alan K., Massy-Westropp, Ralph A., Moss, Gerard P., Weedon, Basil C. L.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1984

Langue:

english

Fichier:

PDF, 1.54 MB

english, 1984

30

Solution structures of DEAD-box RNA chaperones reveal conformational changes and nucleic acid tethering by a basic tail

Anna L. Mallam, Inga Jarmoskaite, Pilar Tijerina, Mark Del Campo, Soenke Seifert, Liang Guo, Rick Russell and Alan M. Lambowitz

Journal:

Proceedings of the National Academy of Sciences

Année:

2011

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2011

31

Kijanimicin. Part 3. Structure and absolute stereochemistry of kijanimicin

Mallams, Alan K., Puar, Mohindar S., Rossman, Randall R., McPhail, Andrew T., Macfarlane, Ronald D., Stephens, Richard L.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1983

Langue:

english

Fichier:

PDF, 4.22 MB

english, 1983

32

Insights into Helicase Evolution from the Specificity and Mechanism of a Dead-Box Protein

Mallam, Anna L., Sidote, David J., Lambowitz, Alan M.

Journal:

Biophysical Journal

Année:

2015

Langue:

english

Fichier:

PDF, 34 KB

english, 2015

33

Semisynthetic aminoglycoside antibacterials. Part 9. Synthesis of novel 1- and 3-substituted and 1- and 3-epi-substituted derivatives of sisomicin and gentamicin from the 1- and 3-oxo-derivatives

Boxler, Dena L., Brambilla, Raymond, Davies, D. Huw, Mallams, Alan K., McCombie, Stuart W., Morton, James B., Reichert, Paul, Vernay, H. Frederick

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1981

Langue:

english

Fichier:

PDF, 2.29 MB

english, 1981

34

Semisynthetic aminoglycoside antibacterials. Part 11. Solution conformations of semisynthetic and naturally occurring aminoglycoside antibiotics

Daniels, Peter J. L., Mallams, Alan K., McCombie, Stuart W., Morton, James B., Nagabhushan, Tatanahalli L., Rane, Dinanath F., Reichert, Paul, Wright, John J.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1981

Langue:

english

Fichier:

PDF, 2.09 MB

english, 1981

35

Special techniques of fast atom bombardment mass spectrometry for the study of oligosaccharide containing macrotetronolide antibiotic, kijanimicin.

PRAMANIK, BIRENDRA N., MALLAMS, ALAN K., BARTNER, P. L., ROSSMAN, R. R., MORTON, J. B., MCGLOTTEN, J. H.

Journal:

The Journal of Antibiotics

Année:

1984

Langue:

english

Fichier:

PDF, 1.78 MB

english, 1984

36

THE SYNTHESIS OF 4"-DEOXYGENTAMICIN C1

MALLAMS, ALAN K., VERNAY, H. FREDERICK, CROWE, DAVID F., DETRE, GEORGE, TANABE, MASATO, YASUDA, DENNIS M.

Journal:

The Journal of Antibiotics

Année:

1973

Langue:

english

Fichier:

PDF, 130 KB

english, 1973

37

Semisynthetic aminoglycoside antibacterials. Part 8. Synthesis of novel pentopyranosyl and pentofuranosyl derivatives of gentamine C1 and C1a

Davies, D. Huw, Kugelman, Max, Lee, Paul, Luce, Charles E., Mallams, Alan K., Morton, James B., Saluja, Surinderjit S., Wright, John J., Detre, George, Tanabe, Masato, Yasuda, Dennis M.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1981

Langue:

english

Fichier:

PDF, 2.12 MB

english, 1981

38

Novel semisynthetic oxo and alkyl macrolide antibacterials and related derivatives

Fishman, Andrew G., Mallams, Alan K., Puar, Mohindar S., Rossman, Randall R., Stephens, Richard L.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1987

Langue:

english

Fichier:

PDF, 2.67 MB

english, 1987

39

The megalomicins. Part III. D-Rhodosamine, a new dimethylamino-sugar

Mallams, Alan K.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1973

Langue:

english

Fichier:

PDF, 772 KB

english, 1973

40

The megalomicins. Part V. Mass spectral studies

Jaret, Robert S., Mallams, Alan K., Vernay, H. Frederick

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1973

Langue:

english

Fichier:

PDF, 1.18 MB

english, 1973

41

ChemInform Abstract: SYNTHESIS OF METHYL GENTOSAMINIDE, METHYL 3-DEOXY-3-METHYLAMINOARABINOPYRANOSIDE, AND RELATED AMINO-SUGARS

COOPER, DAVID J., DAVIES, D. HUW, MALLAMS, ALAN K., YEHASKEL, ALBERT S.

Journal:

Chemischer Informationsdienst

Année:

1975

Fichier:

PDF, 240 KB

1975

42

ChemInform Abstract: THE MEGALOMICINS PART 3, D-RHODOSAMINE, A NEW DIMETHYLAMINO-SUGAR

MALLAMS, ALAN K.

Journal:

Chemischer Informationsdienst

Année:

1973

Fichier:

PDF, 95 KB

1973

43

Semisynthetic aminoglycoside antibacterials. Part 7. Synthesis of novel hexopyranosyl and hexofuranosyl derivatives of gentamine C1 and C1a

Daniels, Peter J. L., Luce, Charles E., Mallams, Alan K., Morton, James B., Saluja, Surinderjit S., Tsai, Hsingan, Weinstein, Jay, Wright, John J., Detre, George, Tanabe, Masato, Yasuda, Dennis M.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1981

Langue:

english

Fichier:

PDF, 1.84 MB

english, 1981

44

The megalomicins. Part IV. The structures of megalomicins A, B, C1, and C2

Jaret, Robert S., Mallams, Alan K., Reimann, Hans

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1973

Langue:

english

Fichier:

PDF, 1.89 MB

english, 1973

45

ChemInform Abstract: MEGALOMICINE 1. MITT. D-RHODOSAMIN, EIN NEUER DIMETHYLAMINOZUCKER 2. MITT. STRUKTUR VON MEGALOMICIN A

MALLAMS, ALAN K., JARET, ROBERT S., REIMANN, HANS

Journal:

Chemischer Informationsdienst. Organische Chemie

Année:

1970

Fichier:

PDF, 129 KB

1970

46

ChemInform Abstract: MEGALOMICINS PART 5, MASS SPECTRAL STUDIES

JARET, ROBERT S., MALLAMS, ALAN K., VERNAY, H. FREDERICK

Journal:

Chemischer Informationsdienst

Année:

1973

Fichier:

PDF, 82 KB

1973

47

ChemInform Abstract: MEGALOMICINE 1. MITT. D-RHODOSAMIN, EIN NEUER DIMETHYLAMINOZUCKER 2. MITT. STRUKTUR VON MEGALOMICIN A

MALLAMS, ALAN K., JARET, ROBERT S., REIMANN, HANS

Journal:

Chemischer Informationsdienst. Organische Chemie

Année:

1970

Fichier:

PDF, 129 KB

1970

48

ChemInform Abstract: MEGALOMICINS PART 5, MASS SPECTRAL STUDIES

JARET, ROBERT S., MALLAMS, ALAN K., VERNAY, H. FREDERICK

Journal:

Chemischer Informationsdienst

Année:

1973

Fichier:

PDF, 82 KB

1973

49

ChemInform Abstract: STRUCTURES OF THE AMINOGLYCOSIDE ANTIBIOTICS 66-40B AND 66-40D PRODUCED BY MICROMONOSPORA INYOENSIS

DAVIES, D. HUW, GREEVES, DIANE, MALLAMS, ALAN K., MORTON, JAMES B., TKACH, RICHARD W.

Journal:

Chemischer Informationsdienst

Année:

1975

Fichier:

PDF, 99 KB

1975

50

ChemInform Abstract: THE MEGALOMICINS PART 4, THE STRUCTURES OF MEGALOMICINS A, B, C1 AND C2

JARET, ROBERT S., MALLAMS, ALAN K., REIMANN, HANS

Journal:

Chemischer Informationsdienst

Année:

1973

Fichier:

PDF, 83 KB

1973